Choose from 1,115 vacation rentals located in Panama City, Panama, Panama. Top filters in Panama City, Panama include Internet / Wifi, Air conditioner, and TV. Prices range from $39 to $12,500 per night. Our most popular vacation rental types near Panama City, Panama are Hotel and RV.

Top vacation rentals in Panama City, Panama

Dine by the palm trees
5.0
Outstanding(77 Reviews)
Condo
 in Panama
Patty’s Charming & quiet Boutique Studio with King bed in Colonial Casco Viejo
3 guests · 1 bath
Kitchen / Kitchenette · Air conditioner · Internet / Wifi

The best choice in Panama City, Panama for Condo, for $95 per night for your (business stay, family stay, couples stay, getaway vacation, etc.)

$$$$
vrbo logo
View deal
Property view
4.7
Outstanding(794 Reviews)
Hotel
 in Panama City
5star
The Santa Maria, a Luxury Collection Hotel & Golf Resort, Panama City
Garden · Pool · Kitchen / Kitchenette

Indulge in a peaceful retreat at The Santa Maria, a Luxury Collection Hotel & Golf Resort, Panama City, our elegant Hotel in Panama City, Panama. Enjoy amenities including Air conditioner, Internet / Wifi and Laundry, and more.

$$$$
booking logo
View deal
Property view
4.1
Excellent(3,328 Reviews)
Hotel
 in Panama City
5star
Decapolis Hotel Panama City
Pool · Kitchen / Kitchenette · Air conditioner

Are you ready to indulge in a relaxing getaway? Our Hotel in Panama City, Panama has everything you need for a rejuvenating stay. Treat yourself to Decapolis Hotel Panama City's exceptional amenities, such as Air conditioner, Internet / Wifi and Laundry.

$$$$
booking logo
View deal
Property view
4.0
Good(245 Reviews)
Hotel
 in Panama City
5star
The Westin Panama
Pool · Pets allowed · Air conditioner

This attractive Hotel in Panama City, Panama, $131 per night for your (business stay, family stay, couples stay, getaway vacation, etc.)

$$$$
booking logo
View deal

Search by amenity

Explore vacation rentals with the most popular amenities in Panama City, Panama

Vacation rentals with internet & wifi in Panama City, Panama

Top floor common terrace with unobstructed views  to the Panama Canal!
5.0
Outstanding(60 Reviews)
Condo
 in Panama City
Patty’s Upscale Bay View Condo with King bed by the Amador Causeway & bicycles
3 guests · 1 bedroom · 1 bath
Kitchen / Kitchenette · Air conditioner · Internet / Wifi

This Condo for $110 in Panama City, Panama, is perfect for your next (business stay, family stay, couples stay, getaway vacation, etc.)

$$$$
vrbo logo
View deal
View onto the living-room from the Master bedroom loft
5.0
Outstanding(71 Reviews)
Condo
 in Panama
Patty’s Stunning and quiet 2-Bdr Loft with K & Q in Historical Casco Viejo
5 guests · 2 bedrooms · 2 baths
Kitchen / Kitchenette · Air conditioner · Internet / Wifi

Are you ready to indulge in a relaxing getaway? Our Condo in Panama City, Panama has everything you need for a rejuvenating stay. Treat yourself to Patty’s Stunning and quiet 2-Bdr Loft with K & Q in Historical Casco Viejo's exceptional amenities, such as Air conditioner, Internet / Wifi and Laundry.

$$$$
vrbo logo
View deal
Property view
4.3
Excellent(47 Reviews)
Hotel
 in Panama City
3star
Sofia's B&B Hostal Boutique
Garden · Pets allowed · Air conditioner

Experience the best of Panama City, Panama with this Hotel available for $70. This property is equipped with amenities including Air conditioner, Internet / Wifi and Laundry, and more.

$$$$
booking logo
View deal
Property view
4.3
Excellent(1,248 Reviews)
Hotel
 in Panama City
5star
Central Hotel Panama Casco Viejo
Garden · Pool · Air conditioner

Experience vacation in Panama City, Panama with our Hotel, Central Hotel Panama Casco Viejo. Enjoy amenities such as Air conditioner, Internet / Wifi and Laundry, and more.

$$$$
booking logo
View deal
city photo
Panama City, Panama

Panama City, Panama travel guide

Let us help you plan your perfect Panama City, Panama vacation. Our travel guide highlights things to do, places to see, favorite vacation rental amenities in Panama City, Panama, and more.

Frequently asked questions

Where Is Panama City Located?

The capital of Panama, respectively named Panama City, is located between the Pacific Ocean entrance of the famous eponymous canal, and the tropical rain forest in the northern part of the country.

What Is Panama City Known For?

Panama City is a modern and progressive metropolis framed by cobblestoned historicism. Cosmopolitan yet colonial, Panama City is the gateway to a tropical paradise as well as urbane vibrancy. Marking the intersection between Latin flavor and western progression, Panama City is the regional center for commerce, trade, administration and politics, as well as a cocktail of chic clubs, elegant restaurants, and shimmering skyscrapers. But if you’re ever wanting to escape from the city commotion, a sandy escape is never too far away.

What to See in Panama City?

  • Panama Viejo: Standing and surviving from times gone by, Panama Viejo is the oldest monument one can find in Panama City. The only remains from the old city of Panama, a city that was founded in 1519 by Spanish colonizer Pedro Arias de Ávila, the golden monument – both in age and color – is a certified UNESCO World Heritage Site, drenched in history and saturated in antiquated beauty.
  • Iglesia del Carmen: Routinely cited as one of the most beautiful buildings in Panama and one of the most visited churches in the country, the Iglesia de Carmen is a Gothic icon that rightfully stands at the center of Panama City. Built in the 20th century, this church is reminiscent of Middle Ages architectural artistry, yet evokes a sense of its native Panamanian heritage.
  • Panama Canal: Who has not heard of one of the most iconic features of the entire country, the Panama Canal? An engineering marvel, the canal stretches up to 77 kilometres and connects the Pacific Ocean and the Atlantic Ocean seamlessly and almost effortlessly. Undoubtedly the most popular attraction in Panama City, the Panama Canal has doubled its capacity and an impressive 14,000 ships cross the waters every year.

Popular Destinations Near Panama City

  • Taboga Island: Bearing the pretty moniker of the “island of flowers,” Taboga Island is often named the number one day trip destination from Panama City. Home to a bounty of nature, the island is plentiful with all the precious treasures that Mother Nature has gifted us from the fun-loving nature of pelicans, golden sandy beaches, to rocky shores that beg visitors to snap their wrists and stone skip to their heart’s content.
  • Coronado: Located west of Panama City, Coronado is a quaint beach town that is still aplomb with all the modern amenities you could wish for. Bearing all the comforts of the city and small beachy pleasures, Coronado truly gives the best of both worlds where one can live the beach bum life during the day and then party the night away in a trendy nightclub until the sun comes up.

Best Neighborhoods in Panama City

  • Casco Viejo: The historic district of Panama City, Casco Viejo is routinely voted as the most popular tourist destination in the city. A UNESCO World Heritage Site, Casco Viejo is composed of an atmospheric network of cobbled streets lined with colorful colonial architecture. Whitewashed walls are splashed with vibrant street art and boutique hotels, while artisanal markers and local cafes sit alongside recently added trendy nightclubs and sophisticated art galleries.
  • El Cangrejo: Typically a residential neighborhood for the middle class, El Cangrejo offers a refreshing insight into the real life of Panama City away from the tourist-filled barrios. Centrally located, this neighborhood is within commutable distances to other areas of the city, but still manages to exude a relaxed air of low maintenance. With restaurants, cafes, offices, pharmacies, and schools, the chance to live like a native Panamanian is all the more real when you tread the lanes of El Cangrejo.

What is the price range for rentals in Panama City, Panama?

Vacation rentals in Panama City, Panama have a price range between $39-$12,500. The average price for rentals in Panama City, Panama is $88 per night.

What are the most popular vacation rental amenities in Panama City, Panama?

  • Internet / Wifi
  • Air conditioner
  • TV

Travel inspiration

Keep exploring