Company
Log inHomeAboutList Your PropertyCareersBlogPress
Support
My TripsTraveler ResourcesTravel TrendsContactFAQSitemap

By subscribing you agree to the privacy policy, terms and to receive marketing emails. You can unsubscribe at any time.

© 2026 VacationRenter

TermsPrivacy
Your Privacy Choices
Privacy Choices
Home/United States/South Carolina/Pickens County

Vacation Rentals in Pickens County, SC

Search the perfect vacation rental

Property type

Popular amenities

Choose from 1,270 vacation rentals located in Pickens County, South Carolina. Top filters in Pickens County include Non-smoking, Family friendly, and No pets allowed. Prices range from $56 to $6,189 per night. Our most popular vacation rental types near Pickens County are House and Hotel.

Top vacation rentals in Pickens County

Exterior
9.9 / 10
Outstanding(294 Ratings)
Peace-in-the-Forest Retreat - Singles, Couples, Artists, Forest Lovers
Cabin
 in Pickens
4 guests · 1 bedroom · 1 bath

Looking to create some memories in Pickens County? Look no further than our Cabin, Peace-in-the-Forest Retreat - Singles, Couples, Artists, Forest Lovers. Enjoy top-rated amenities including ;, and more.

$$$$
vrbo logo
View deal
Bedroom
8.2 / 10
Excellent(438 Ratings)
Comfort Inn & Suites Clemson - University Area
Hotel
 in Clemson
4star
2 guests · 1 bedroom · 1 bath

Looking for a business stay, family stay, couples stay, getaway vacation, or traveling to Pickens County, at $316 per night for your next great vacation.

$$$$
booking logo
View deal
Property logo or sign
9.2 / 10
Outstanding(195 Ratings)
James F. Martin Inn
Hotel
 in Clemson
3star
2 guests · 1 bedroom · 1 bath

Indulge in a peaceful retreat at James F. Martin Inn, our elegant Hotel in Pickens County. Enjoy amenities including ;, and more.

$$$$
booking logo
View deal
Pool view, Swimming pool, Swimming pool
8.8 / 10
Excellent(1,030 Ratings)
Lakeside Lodge Clemson
Hotel
 in Clemson
2 guests · 1 bedroom · 1 bath

This Hotel in Pickens County, is the right price for your (business stay, family stays, couples stay, getaway vacation, etc.) today!

$$$$
booking logo
View deal

Travel inspiration

Keep exploring

  • View All Countries
  • United States
  • Argentina
  • Australia
  • Austria
  • Belgium
  • Brazil
  • Canada
  • Colombia
  • Czechia
  • Denmark
  • Finland
  • France
  • Germany
  • Greece
  • Hungary
  • India
  • Ireland
  • Italy
  • Mexico
  • Netherlands
  • New Zealand
  • Norway
  • Philippines
  • Poland
  • Portugal
  • Romania
  • South Africa
  • Spain
  • Sweden
  • Switzerland
  • United Kingdom
  • View All States
  • Alabama
  • Alaska
  • Arizona
  • Arkansas
  • California
  • Colorado
  • Connecticut
  • Delaware
  • Florida
  • Georgia
  • Hawaii
  • Idaho
  • Illinois
  • Indiana
  • Iowa
  • Kansas
  • Kentucky
  • Louisiana
  • Maine
  • Maryland
  • Massachusetts
  • Michigan
  • Minnesota
  • Mississippi
  • Missouri
  • Montana
  • Nebraska
  • Nevada
  • New Hampshire
  • New Jersey
  • New Mexico
  • Orange Beach, US
  • Breckenridge, US
  • Destin, US
  • Park City, US
  • Miramar Beach, US
  • Panama City Beach, US
  • W Beach Blvd, US
  • Key West, US
  • Vail, US
  • Kaanapali, US
  • Ocean City, US
  • Big Sky, US
  • Hilton Head Island, US
  • Marco Island, US
  • Steamboat Springs, US
  • Seaside, US
  • Isle of Palms, US
  • Princeville, US
  • Folly Beach, US
  • Mammoth Lakes, US
  • North Myrtle Beach, US
  • Utah, US
  • Rosemary Beach, US
  • Paris, FR
  • Copper Mountain, US
  • Snowmass Village, US
  • Seagrove Beach, US
  • Puako, US
  • Telluride, US
  • City of Westminster, UK
  • Whitefish, US
  • Gatlinburg, US
  • Dubai, AE
  • Halkidiki, GR
  • Orange Beach, US
  • Key West, US
  • Istanbul, Türkiye
  • Ocean City, US
  • Honolulu, US
  • Cape Town, ZA
  • Panama City Beach, US
  • East Attica Regional Unit, GR
  • W Beach Blvd, US
  • Myrtle Beach, US
  • Abu Dhabi, AE
  • Makarska, HR
  • Eilat, IL
  • Poreč, HR
  • Miramar Beach, US
  • Treasure Island, US
  • Virginia Beach, US
  • North Myrtle Beach, US
  • Kaanapali, US
  • Kapalua, US
  • Portorož, SI
  • Marco Island, US
  • Messenia, GR
  • Pa Tong, TH
  • Cape May, US
  • Nassau, BS
  • Destin, US
  • Taormina, IT
  • Paphos, CY
  • Funchal, PT
  • Big Sky, US
  • Zakopane, PL
  • Zermatt, CH
  • St Anton am Arlberg, AT
  • Falls Creek, AU
  • Kitzbuhel, AT
  • Park City, US
  • Vail, US
  • Québec City, CA
  • Les Allues, FR
  • Zell am See, AT
  • Hakuba, JP
  • Mansfield, AU
  • Mammoth Lakes, US
  • Breckenridge, US
  • Mayrhofen, AT
  • Queenstown, NZ
  • Banff, CA
  • Telluride, US
  • Piesendorf, AT
  • Interlaken, CH
  • Mountain Village, US
  • Schladming, AT
  • Snowmass Village, US
  • Utah, US
  • Soelden, AT
  • Nozawaonsen, JP
  • Niseko, JP
  • Whitefish, US
  • Beaver Creek, US
  • Lake Louise, CA
  • Bright, AU
  • B&Bs
  • Cabins
  • Condos
  • Cottages
  • Hostels
  • Hotels
  • Houses
  • Lodges
  • Motels
  • Resorts
  • Villas

Search by property type

property-type
Cabin
property-type
Cottage
property-type
Villa

Search by amenity

Explore vacation rentals with the most popular amenities in Pickens County

city photo
Pickens County

Pickens County travel guide

Let us help you plan your perfect Pickens County vacation. Our travel guide highlights things to do, places to see, favorite vacation rental amenities in Pickens County, and more.

Explore near Pickens County

Related vacation destinations

Blue Ridge Mountains vacation rentals
Avg. $275 · 173,329 properties
Ozark Mountains vacation rentals
Avg. $206 · 50,914 properties
Maui vacation rentals
Avg. $461 · 27,640 properties
Panama City Beach vacation rentals
Avg. $295 · 23,147 properties
Jersey Shore vacation rentals
Avg. $411 · 22,944 properties
Long Island vacation rentals
Avg. $396 · 21,503 properties
Tampa Bay vacation rentals
Avg. $295 · 20,059 properties
Hudson Valley vacation rentals
Avg. $336 · 19,895 properties
Hilton Head Island vacation rentals
Avg. $358 · 18,583 properties
Myrtle Beach vacation rentals
Avg. $205 · 18,581 properties
North Myrtle Beach vacation rentals
Avg. $306 · 15,529 properties
Charleston vacation rentals
Avg. $372 · 6,231 properties

Frequently asked questions

What are the top travel destinations in Pickens County

Lake Keowee, Clemson, and Lake Jocassee are the top three destinations to travel in Pickens County.

What is the price range for rentals in Pickens County?

Vacation rentals in Pickens County have a price range between $56-$6,189. The average price for rentals in Pickens County is $291 per night.

How many cities have available rentals in Pickens County?

There are 5 destinations with available rentals in Pickens County.

Nearby vacation destinations

Anderson vacation rentals
Avg. $166 · 87 properties
Brevard vacation rentals
Avg. $202 · 305 properties
Clemson vacation rentals
Avg. $511 · 178 properties
Flat Rock vacation rentals
Avg. $183 · 185 properties
Gloucester vacation rentals
Avg. $268 · 202 properties
Greenville vacation rentals
Avg. $177 · 1,102 properties
Greer vacation rentals
Avg. $155 · 509 properties
Lake Jocassee vacation rentals
Avg. $639 · 14 properties
Lake Keowee vacation rentals
Avg. $404 · 849 properties
Pisgah Forest vacation rentals
Avg. $193 · 61 properties
Seneca vacation rentals
Avg. $247 · 114 properties
Travelers Rest vacation rentals
Avg. $179 · 76 properties