Hotel in Rome
3-Star Hotel
Reasons to book
Guests love it hereGuests give this property a top rating
Top-tier experienceA high end property in this area
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About this hotel
Just 220 yards from St Peter’s Basilica, Sant’Anna Hotel is a 17th-century building offering elegant rooms and interiors in central Rome. Wi-Fi is free and a varied continental breakfast is available.
Amenities
Airport transportation available
Shuttle available
Concierge services
Free WiFi/internet
Air conditioning
Non-smoking
Heating
WiFi/Internet
Garden
Family friendly
Safe
Accessible by lift
Key access
Housekeeping available
Fire alarm
Fire extinguisher
Cleaning products
Map of Rome
Nearby attractions
Available Rooms
Ratings and reviews
100% verified reviews10 / 10Outstanding·Sep 2026
Beautiful hotel in the heart of the Vatican neighborhood, close to shops and restaurants, as well as walking distance to St. Peter’s Basilica, Castel de St. Angelo the bridge of angels, and Piazza Navona.
This hotel’s decor is classic Italian, with cozy rooms, modern baths, and a lovely garden sitting area! Wonderful and friendly, helpful employees!
We love the property and hope to stay again in the future!
10 / 10Outstanding·Aug 2026
Breakfast was wonderful. A nice variety, fruit was fresh and so were the pastries. The staff was welcoming and helpful.
10 / 10Outstanding·Aug 2026
My second time staying here it is the best hotel near the Vatican,the room we had was spotless ,love the marble bathroom,the lobby is also beautiful with a small garden patio outside,we had a tea kettle with tea and instant coffee ,the room had air-conditioning which was very much appreciated with the heat wave this summer,also a mini fridge provided.
The only thing I didn't like was giving the key to the front desk every time I left the building,felt kind of like a 12 year old .
5 / 10·Aug 2026
The LOCATION- right near the St Peter's Basilica- so near the Vatican.
Our stay was okay overall, but the location was definitely the highlight. It was amazing—however, I actually found another hotel on the same street that had a much better atmosphere and energy.
The rooms are extremely close to each other, and the doors are very noisy because they require a lot of force to open and close. The hotel also uses large traditional keys for the rooms and a card system for the lights, which felt a bit outdated.
Unfortunately, our experience with the noise complaints was very disappointing. My teenagers told me that while they were in the room, someone knocked very loudly on the door, and of course they did not open it. About 10 minutes later, after we arrived, we were simply talking normally when someone knocked loudly on the door again. We did not open it, and the whole situation started to feel uncomfortable—almost like something you would see in a cheap hotel movie. Later, there was another small knock, and we still did not open the door. Shortly after, the front desk called to inform us that they had received two noise complaints. I explained firmly that we were already in bed at that point.
I was very disappointed with how the situation was handled. It felt like the hotel prioritized other guests’ complaints without considering our side of the story, perhaps because we were traveling with teenagers. If the hotel is intended for guests who prefer complete silence, no teens allowed, they should clearly state that. They should also be transparent about how close the rooms are to each other, since normal conversations can easily be heard.
Because of this experience, I would not stay here again or recommend this hotel to others. The breakfast also lacked variety, and considering the price we paid, I expected much more—similar to the quality and selection I experienced at hotels in Venice, Florence, or even Naples.
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Top rated by guests
9.1Outstanding
(683 Ratings)
"Beautiful hotel in the heart of the Vatican neighborhood, close to shops and restaurants, as well as walking distance to St. Peter’s Basilica, Castel de St. Angelo the bridge of angels, and Piazza Nav..."
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