Hotel in Rome
3-Star Hotel
Reasons to book
Guests love it hereGuests give this property a top rating
Top-tier experienceA high end property in this area
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About this hotel
Just 220 yards from St Peter’s Basilica, Sant’Anna Hotel is a 17th-century building offering elegant rooms and interiors in central Rome. Wi-Fi is free and a varied continental breakfast is available.
Amenities
Airport transportation available
Shuttle available
Concierge services
Free WiFi/internet
Air conditioning
Non-smoking
Heating
WiFi/Internet
Garden
Family friendly
Safe
Accessible by lift
Key access
Housekeeping available
Fire alarm
Fire extinguisher
Cleaning products
Map of Rome
Available Rooms
Ratings and reviews
100% verified reviews7 / 10Good·Oct 2026
Wonderful staff
Nada
9 / 10Outstanding·Oct 2026
Lovely, cosy, traditional Italian hotel in a great location. Having stayed in other locations previously, this was good for everything. Right by the Vatican, close to Castel St Angelo, 20 minutes walk to The Trevi Fountain and The Pantheon, a short taxi to The Colosseum. We loved our balcony, wonderfully spacious bathroom with plenty of towels.
My niece and nephew loved the gelateria literally on site! One of the better ones too!
Breakfast had everything you could want and need, including fresh pancakes and waffles by the lovely lady. Served early too, which is always a plus.
Hotel helped with a taxi to and from the airport.
Being very picky, a body lotion in the bathroom and travel slippers would be nice (but I travel with some, so not an issue), also bottled water on the house, or at least filtered water, again being fussy!
9 / 10Outstanding·Oct 2026
The hotel is in a great location. Rome is as accessible as walking or a short taxi ride. The Vatican is less than a 10 minute walk. The area is lively with restaurants and shops during the day, and quiet at night. The hotel is historic with modern amenities. Hotel staff is friendly, knowledgeable and welcoming. Breakfast was delicious and competitive with outside restaurants. Would definitely stay here again.
Can't think of anything to mention.
5 / 10·Aug 2026
The LOCATION- right near the St Peter's Basilica- so near the Vatican.
Our stay was okay overall, but the location was definitely the highlight. It was amazing—however, I actually found another hotel on the same street that had a much better atmosphere and energy.
The rooms are extremely close to each other, and the doors are very noisy because they require a lot of force to open and close. The hotel also uses large traditional keys for the rooms and a card system for the lights, which felt a bit outdated.
Unfortunately, our experience with the noise complaints was very disappointing. My teenagers told me that while they were in the room, someone knocked very loudly on the door, and of course they did not open it. About 10 minutes later, after we arrived, we were simply talking normally when someone knocked loudly on the door again. We did not open it, and the whole situation started to feel uncomfortable—almost like something you would see in a cheap hotel movie. Later, there was another small knock, and we still did not open the door. Shortly after, the front desk called to inform us that they had received two noise complaints. I explained firmly that we were already in bed at that point.
I was very disappointed with how the situation was handled. It felt like the hotel prioritized other guests’ complaints without considering our side of the story, perhaps because we were traveling with teenagers. If the hotel is intended for guests who prefer complete silence, no teens allowed, they should clearly state that. They should also be transparent about how close the rooms are to each other, since normal conversations can easily be heard.
Because of this experience, I would not stay here again or recommend this hotel to others. The breakfast also lacked variety, and considering the price we paid, I expected much more—similar to the quality and selection I experienced at hotels in Venice, Florence, or even Naples.
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Top rated by guests
9.1Outstanding
(683 Ratings)
"The property was well taken care of and centrally located. Walking distance to the Vatican and saint Peter’s cathedral.
Restaurant right outside too!"
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